Ottestad, William Arne; Rognes, Ingrid Nygren; Pischke, Søren; Mollnes, Tom Eirik; Andersson, Ulf; Eken, Torsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08)
<i>Objective</i>: The causal role of the prototype alarmin high mobility group box 1 protein (HMGB1) in systemic
inflammation and remote organ injury after trauma and shock is established in animal models but not in humans. Our
aim was therefore to determine HMGB1 concentration kinetics with high time resolution during the first hours after
trauma in individual patients, and investigate the ...